{"id":2077,"date":"2023-03-29T11:07:47","date_gmt":"2023-03-29T15:07:47","guid":{"rendered":"https:\/\/herpescureadvocacy.com\/?p=2077"},"modified":"2023-03-29T11:07:47","modified_gmt":"2023-03-29T15:07:47","slug":"promising-progress-in-clinical-trials-for-pritelivir","status":"publish","type":"post","link":"https:\/\/herpescureadvocacy.com\/2023\/03\/29\/promising-progress-in-clinical-trials-for-pritelivir\/","title":{"rendered":"Promising Progress in clinical trials for Pritelivir"},"content":{"rendered":"\n

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\"five<\/figure>\n<\/div>\n\n\n

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Positive news abounds for the Aicuris<\/a> team, and patients living with HSV, with the release of new results from their Phase three clinical trials for Pritelivir<\/a> and initiation of a new clinical trial studying the use of Pritelivir in healthy patients.<\/p>\n\n\n\n

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Pritelivir was found to be safe and well tolerated up to 600 mg following single and up to 200 mg following multiple once-daily doses. Considering a therapeutic dose of 100 mg once-daily, Pritelivir demonstrated a favorable safety and tolerability and pharmacokinetic profile in healthy subjects to support further development. <\/p>\n\n\n\n

Read the results here: First-in-Human, Single- and Multiple-Ascending-Dose, Food-Effect, and Absolute Bioavailability Trials to Assess the Pharmacokinetics, Safety, and Tolerability of Pritelivir, a Nonnucleoside Helicase-Primase Inhibitor Against Herpes Simplex Virus in Healthy Subjects<\/a><\/p>\n\n\n\n

In exciting, if long-awaited news for patients globally, AiCuris has also initiated a new clinical study that has commenced testing Pritelivir in healthy, immune competent patients. AiCuris had previously been studying Pritelivir among immunocompromised for several years and are currently in Phase three. It is widely assumed it\u2019ll be approved for immunocompromised soon, potentially in 2024, and the FDA has already granted breakthrough designation streamlining the process for approval. <\/p>\n\n\n\n

Clinical Trial for new Herpes Simplex Virus Treatment<\/h2>\n\n\n\n

With the positive results from the initial safety studies in the immunocompromised – this trial would likely be the start of a move to bring the to the general population. Read more and apply to participate (note the study location in London, England) here: Pritelivir Study In Healthy Individuals<\/a><\/strong>. The new clinical trial for Pritelivir in health patients ends in May 2023 (five months of study) so AiCuris is moving quickly on Phase one – likely with recent learnings from the earlier trial. <\/p>\n\n\n\n\n\n

TIP LINE: info@herpescureadvocacy.com<\/a><\/p>\n<\/div>\n\n\n\n

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Positive news abounds for the Aicuris team, and patients living with HSV, with the release of new results from their Phase three clinical trials for Pritelivir and initiation of aContinue reading “Promising Progress in clinical trials for Pritelivir”<\/span><\/a><\/p>\n","protected":false},"author":205069572,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_coblocks_attr":"","_coblocks_dimensions":"","_coblocks_responsive_height":"","_coblocks_accordion_ie_support":"","_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_feature_clip_id":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"{title}\n\n{excerpt}\n\n{url}","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2},"_wpas_customize_per_network":false,"jetpack_post_was_ever_published":false},"categories":[1],"tags":[],"class_list":["post-2077","post","type-post","status-publish","format-standard","hentry","category-uncategorized","entry"],"yoast_head":"\nPromising Progress in clinical trials for Pritelivir - 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Pritelivir is a highly anticipated new treatment for resistant Herpes Simplex Virus infections that cannot be managed with the available anti-virals. It is currently being tested for immune compromised patients only and, if proven safe\u2026","rel":"","context":"In "Advocacy"","block_context":{"text":"Advocacy","link":"https:\/\/herpescureadvocacy.com\/category\/advocacy\/"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2021\/10\/img_1044.jpg?fit=1000%2C638&ssl=1&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2021\/10\/img_1044.jpg?fit=1000%2C638&ssl=1&resize=350%2C200 1x, https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2021\/10\/img_1044.jpg?fit=1000%2C638&ssl=1&resize=525%2C300 1.5x, https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2021\/10\/img_1044.jpg?fit=1000%2C638&ssl=1&resize=700%2C400 2x"},"classes":[]},{"id":4168,"url":"https:\/\/herpescureadvocacy.com\/2024\/07\/24\/impressions-from-ihw-2024\/","url_meta":{"origin":2077,"position":1},"title":"Impressions from IHW 2024","author":"Patient Advocate","date":"July 24, 2024","format":false,"excerpt":"This year\u2019s conference highlighted several innovative studies focusing on interventions and antivirals targeting Herpes Simplex Viruses (HSV). Below, we summarize the key findings and their potential impacts on the treatment of HSV infections. Gene Editing Therapy for HSV One of the most promising developments presented was a gene editing therapy\u2026","rel":"","context":"With 1 comment","block_context":{"text":"With 1 comment","link":"https:\/\/herpescureadvocacy.com\/2024\/07\/24\/impressions-from-ihw-2024\/#comments"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2024\/07\/Screenshot-2024-07-24-075548.png?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2024\/07\/Screenshot-2024-07-24-075548.png?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2024\/07\/Screenshot-2024-07-24-075548.png?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2024\/07\/Screenshot-2024-07-24-075548.png?resize=700%2C400&ssl=1 2x, https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2024\/07\/Screenshot-2024-07-24-075548.png?resize=1050%2C600&ssl=1 3x"},"classes":[]},{"id":1469,"url":"https:\/\/herpescureadvocacy.com\/2022\/12\/01\/meet-the-experts\/","url_meta":{"origin":2077,"position":2},"title":"Meet the Experts","author":"Patient Advocate","date":"December 1, 2022","format":false,"excerpt":"A series of talks with experts in herpes simplex virus research, commercial partners in vaccine or treatment development, sexual health, and more. Learn more about clinical trials, the latest science, advances in technology, and the role of patient advocacy. UPenn\/BioNTech Clinical Trials: Latest updates and Q&A with Dr Harvey Friedman\u2026","rel":"","context":"With 1 comment","block_context":{"text":"With 1 comment","link":"https:\/\/herpescureadvocacy.com\/2022\/12\/01\/meet-the-experts\/#comments"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2021\/10\/img_1044.jpg?fit=1000%2C638&ssl=1&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2021\/10\/img_1044.jpg?fit=1000%2C638&ssl=1&resize=350%2C200 1x, https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2021\/10\/img_1044.jpg?fit=1000%2C638&ssl=1&resize=525%2C300 1.5x, https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2021\/10\/img_1044.jpg?fit=1000%2C638&ssl=1&resize=700%2C400 2x"},"classes":[]},{"id":1018,"url":"https:\/\/herpescureadvocacy.com\/2022\/03\/17\/herpes-cure-pipeline-2-0-2\/","url_meta":{"origin":2077,"position":3},"title":"Herpes Cure Pipeline 2.0","author":"Patient Advocate","date":"March 17, 2022","format":false,"excerpt":"Pipeline for a Herpes Cure We track the timelines for preclinical and clinical study, formulation updates, and go-to market strategies with research teams globally. The pipeline only includes teams with published data, and those with expressed interest of bringing a product to market. There is no other organization globally except\u2026","rel":"","context":"With 20 comments","block_context":{"text":"With 20 comments","link":"https:\/\/herpescureadvocacy.com\/2022\/03\/17\/herpes-cure-pipeline-2-0-2\/#comments"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2022\/03\/image.jpg?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2022\/03\/image.jpg?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2022\/03\/image.jpg?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2022\/03\/image.jpg?resize=700%2C400&ssl=1 2x"},"classes":[]},{"id":6655,"url":"https:\/\/herpescureadvocacy.com\/2026\/01\/06\/from-discovery-to-cure-understanding-the-complex-path-of-antiherpetic-drug-development\/","url_meta":{"origin":2077,"position":4},"title":"From Discovery to Cure: Understanding the Complex Path of Antiherpetic Drug Development","author":"Patient Advocate","date":"January 6, 2026","format":false,"excerpt":"We often hear headlines about breakthrough discoveries and promising new therapies for herpes \u2014 only to hear nothing more about them months or even years later. Why do so many promising antiherpetic drugs fail to reach patients? Why does drug development take so long, and where are the biggest bottlenecks?\u2026","rel":"","context":"In "Herpes Cure Research"","block_context":{"text":"Herpes Cure Research","link":"https:\/\/herpescureadvocacy.com\/category\/herpes-cure\/"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2026\/01\/img_3101.jpg?fit=851%2C315&ssl=1&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2026\/01\/img_3101.jpg?fit=851%2C315&ssl=1&resize=350%2C200 1x, https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2026\/01\/img_3101.jpg?fit=851%2C315&ssl=1&resize=525%2C300 1.5x, https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2026\/01\/img_3101.jpg?fit=851%2C315&ssl=1&resize=700%2C400 2x"},"classes":[]},{"id":4139,"url":"https:\/\/herpescureadvocacy.com\/2024\/07\/24\/terri-warren-qa-recording\/","url_meta":{"origin":2077,"position":5},"title":"Terri Warren Q&A Recording","author":"Patient Advocate","date":"July 24, 2024","format":false,"excerpt":"We had a great turnout at our webinar last week featuring Terri Warren and her preliminary data from her Herpes survey. Thank you to everyone who joined and brought all of their questions! This webinar was recorded and is provided at the link below for anyone who was unable to\u2026","rel":"","context":"Similar post","block_context":{"text":"Similar post","link":""},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2023\/05\/Board-Head-shots.png?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2023\/05\/Board-Head-shots.png?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2023\/05\/Board-Head-shots.png?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2023\/05\/Board-Head-shots.png?resize=700%2C400&ssl=1 2x"},"classes":[]}],"_links":{"self":[{"href":"https:\/\/herpescureadvocacy.com\/wp-json\/wp\/v2\/posts\/2077","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/herpescureadvocacy.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/herpescureadvocacy.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/herpescureadvocacy.com\/wp-json\/wp\/v2\/users\/205069572"}],"replies":[{"embeddable":true,"href":"https:\/\/herpescureadvocacy.com\/wp-json\/wp\/v2\/comments?post=2077"}],"version-history":[{"count":8,"href":"https:\/\/herpescureadvocacy.com\/wp-json\/wp\/v2\/posts\/2077\/revisions"}],"predecessor-version":[{"id":2098,"href":"https:\/\/herpescureadvocacy.com\/wp-json\/wp\/v2\/posts\/2077\/revisions\/2098"}],"wp:attachment":[{"href":"https:\/\/herpescureadvocacy.com\/wp-json\/wp\/v2\/media?parent=2077"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/herpescureadvocacy.com\/wp-json\/wp\/v2\/categories?post=2077"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/herpescureadvocacy.com\/wp-json\/wp\/v2\/tags?post=2077"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}