{"id":2124,"date":"2023-04-01T17:05:07","date_gmt":"2023-04-01T21:05:07","guid":{"rendered":"https:\/\/herpescureadvocacy.com\/?page_id=2124"},"modified":"2026-05-05T21:40:20","modified_gmt":"2026-05-06T01:40:20","slug":"herpes-simplex-virus-101-the-basics","status":"publish","type":"page","link":"https:\/\/herpescureadvocacy.com\/herpes-simplex-virus-101-the-basics\/","title":{"rendered":"Herpes Simplex Virus 101: The Basics"},"content":{"rendered":"\n<figure class=\"wp-block-image size-large\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" width=\"750\" height=\"250\" data-attachment-id=\"2126\" data-permalink=\"https:\/\/herpescureadvocacy.com\/herpes-simplex-virus-101-the-basics\/untitled-design-2\/\" data-orig-file=\"https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2023\/04\/Untitled-design.png?fit=1200%2C400&amp;ssl=1\" data-orig-size=\"1200,400\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;,&quot;orientation&quot;:&quot;0&quot;}\" data-image-title=\"Untitled-design\" data-image-description=\"\" data-image-caption=\"\" data-large-file=\"https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2023\/04\/Untitled-design.png?fit=750%2C250&amp;ssl=1\" src=\"https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2023\/04\/Untitled-design.png?resize=750%2C250&#038;ssl=1\" alt=\"\" class=\"wp-image-2126\" srcset=\"https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2023\/04\/Untitled-design.png?resize=1024%2C341&amp;ssl=1 1024w, https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2023\/04\/Untitled-design.png?resize=300%2C100&amp;ssl=1 300w, https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2023\/04\/Untitled-design.png?resize=768%2C256&amp;ssl=1 768w, https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2023\/04\/Untitled-design.png?w=1200&amp;ssl=1 1200w\" sizes=\"auto, (max-width: 750px) 100vw, 750px\" \/><\/figure>\n\n\n\n<div class=\"wp-block-group\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><em>The basics on the prevalence, epidemiology, and public health impact of Herpes Simplex Virus. <\/em><\/p>\n\n\n\n<h1 class=\"wp-block-heading\">Prevalence, Demographics, and Data on Herpes Simplex Virus <\/h1>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/www.cdc.gov\/nchs\/data\/databriefs\/db304.pdf\">2018 NCHS Data Brief: Prevalence of Herpes Simplex Virus Type 1 and Type 2 in<br>Persons Aged 14\u201349: United States, 2015\u20132016<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/www.std.uw.edu\/go\/comprehensive-study\/genital-herpes\/core-concept\/all#page-title\">National STD Training Curriculum on Herpes from NSTDC<\/a><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-group\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<h1 class=\"wp-block-heading\"><strong>Association with HIV\/AIDS<\/strong><\/h1>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/herpescureadvocacy.com\/genital-herpes-and-hiv-aids-related-epidemics\/\">Genital Herpes and HIV: Related Epidemics<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/www.nih.gov\/news-events\/nih-research-matters\/why-genital-herpes-boosts-risk-hiv-infection\">Why Genital Herpes boosts the risk of HIV infection<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/academic.oup.com\/cid\/article\/43\/3\/347\/333493?login=false\">Management of Herpes Simplex Virus Type 2 Infection in HIV Type 1\u2013Infected Persons<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/apps.who.int\/iris\/bitstream\/handle\/10665\/312344\/9789241515580-eng.pdf\">WHO Report: The risk of HIV acquisition is approximately tripled<\/a><\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" width=\"750\" height=\"324\" data-attachment-id=\"2142\" data-permalink=\"https:\/\/herpescureadvocacy.com\/herpes-simplex-virus-101-the-basics\/screenshot-2023-04-01-141218\/\" data-orig-file=\"https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2023\/04\/Screenshot-2023-04-01-141218.png?fit=1352%2C584&amp;ssl=1\" data-orig-size=\"1352,584\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;,&quot;orientation&quot;:&quot;0&quot;}\" data-image-title=\"Screenshot-2023-04-01-141218\" data-image-description=\"\" data-image-caption=\"\" data-large-file=\"https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2023\/04\/Screenshot-2023-04-01-141218.png?fit=750%2C324&amp;ssl=1\" src=\"https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2023\/04\/Screenshot-2023-04-01-141218.png?resize=750%2C324&#038;ssl=1\" alt=\"\" class=\"wp-image-2142\" srcset=\"https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2023\/04\/Screenshot-2023-04-01-141218.png?resize=1024%2C442&amp;ssl=1 1024w, https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2023\/04\/Screenshot-2023-04-01-141218.png?resize=300%2C130&amp;ssl=1 300w, https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2023\/04\/Screenshot-2023-04-01-141218.png?resize=768%2C332&amp;ssl=1 768w, https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2023\/04\/Screenshot-2023-04-01-141218.png?resize=1200%2C518&amp;ssl=1 1200w, https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2023\/04\/Screenshot-2023-04-01-141218.png?w=1352&amp;ssl=1 1352w\" sizes=\"auto, (max-width: 750px) 100vw, 750px\" \/><\/figure>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-group\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<div class=\"wp-block-group\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<h1 class=\"wp-block-heading\"><strong>Neonatal Herpes<\/strong><\/h1>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/16505733\/\">The public health imperative for a neonatal herpes simplex virus infection surveillance system<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/15319088\/\">Neonatal herpes should be a reportable disease<\/a><\/p>\n<\/div><\/div>\n<\/div><\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<div class=\"wp-block-group\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<h1 class=\"wp-block-heading\"><strong>Herpes and Neurodegenerative Disease<\/strong><\/h1>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/www.hopkinsmedicine.org\/neurology_neurosurgery\/centers_clinics\/encephalitis\/\">The Encephalitis Center at Johns Hopkins<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/encephalitis.ucsf.edu\/\">UCSF Center for Encephalitis and Meningitis<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/link.springer.com\/article\/10.1007\/s13365-021-01012-9\">How an increase in the copy number of HSV-1 during latency can cause Alzheimer\u2019s disease: the viral and cellular dynamics according to the microcompetition model<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/jamanetwork.com\/journals\/jamaneurology\/fullarticle\/795486\">Neurological Complications of Herpes Simplex Virus Type 2 Infection<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S1474442207702673\">The neurotropic herpes viruses: herpes simplex and varicella-zoster<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/www.frontiersin.org\/articles\/10.3389\/fncel.2019.00046\/full\">Herpes Simplex Virus Type 1 Infection of the Central Nervous System: Insights Into Proposed Interrelationships With Neurodegenerative Disorders<\/a><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-group\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<h1 class=\"wp-block-heading\"><strong>Public Health Guidelines for Herpes<\/strong><\/h1>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/www.cdc.gov\/std\/treatment-guidelines\/herpes.htm\">2021 <\/a><span><a href=\"https:\/\/www.cdc.gov\/std\/treatment-guidelines\/herpes.htm\">CDC STI Treatment Guidelines and guidance on Herpes Screening<\/a><\/span><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/www.uspreventiveservicestaskforce.org\/uspstf\/recommendation\/genital-herpes-serologic-screening\">USPSTF Guidelines for Testing for Herpes<\/a><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-group\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<h1 class=\"wp-block-heading\">Reports on Herpes Simplex Virus<\/h1>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/www.who.int\/publications-detail-redirect\/9789241515580\">WHO Preferred Product Characteristics for Herpes Simplex Virus Vaccines<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/nap.nationalacademies.org\/read\/25955\/chapter\/1\">National Academy of Science Engineering and Medicine 2021 STI REPORT<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/www.hhs.gov\/sites\/default\/files\/STI-National-Strategic-Plan-2021-2025.pdf\">US Department of Health and Human Services 2020 HSV STI Report<\/a><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-group\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<h1 class=\"wp-block-heading\">Performance of Herpes Tests<\/h1>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28876290\/\">Performance of Commercial Enzyme-Linked Immunoassays for Diagnosis of Herpes Simplex Virus-1 and Herpes Simplex Virus-2 Infection in a Clinical Setting (2017)<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S073288931930570X?via%3Dihub\">Herpes simplex virus type 2 (HSV-2) IgG index values in two immunoassays in relation to HSV-2 IgG inhibition assay results (2019)<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/journals.lww.com\/stdjournal\/Citation\/2022\/05000\/Characterization_of_Serum_Samples_With_Discordant.6.aspx\">Characterization of Serum Samples With Discordant Results in 2 Herpes Simplex Virus Type 2 IgG Assays 2022<\/a><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-group\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<div class=\"wp-block-group\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<h1 class=\"wp-block-heading\">Current s<strong>tatus of Herpes cure, treatment and vaccine research<\/strong><\/h1>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4106293\/\">Current status and prospects for development of an HSV vaccine<\/a> (2015)<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/herpescureresearch.files.wordpress.com\/2022\/03\/hsv-research-pipeline_2.0_as-of-3-20-2022.pdf\">Herpes Cure Advocacy: Herpes Cure Pipeline 2.0<\/a> (As of March 2022)<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1931524420300414?via%3Dihub\">Vaccines to prevent genital herpes &#8211; ScienceDirect<\/a> (2020)<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26973067\/\">Status of vaccine research and development of vaccines for herpes simplex virus &#8211; PubMed (nih.gov)<\/a> (2016)<\/p>\n\n\n\n<div class=\"wp-block-media-text is-stacked-on-mobile\"><figure class=\"wp-block-media-text__media\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" width=\"750\" height=\"319\" data-attachment-id=\"1921\" data-permalink=\"https:\/\/herpescureadvocacy.com\/home-2\/screenshot-7-1\/\" data-orig-file=\"https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2023\/01\/Screenshot-7-1.png?fit=1133%2C481&amp;ssl=1\" data-orig-size=\"1133,481\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;,&quot;orientation&quot;:&quot;0&quot;}\" data-image-title=\"Screenshot-7-1\" data-image-description=\"\" data-image-caption=\"\" data-large-file=\"https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2023\/01\/Screenshot-7-1.png?fit=750%2C319&amp;ssl=1\" src=\"https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2023\/01\/Screenshot-7-1.png?resize=750%2C319&#038;ssl=1\" alt=\"\" class=\"wp-image-1921 size-full\" srcset=\"https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2023\/01\/Screenshot-7-1.png?resize=1024%2C435&amp;ssl=1 1024w, https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2023\/01\/Screenshot-7-1.png?resize=300%2C127&amp;ssl=1 300w, https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2023\/01\/Screenshot-7-1.png?resize=768%2C326&amp;ssl=1 768w, https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2023\/01\/Screenshot-7-1.png?w=1133&amp;ssl=1 1133w\" sizes=\"auto, (max-width: 750px) 100vw, 750px\" \/><\/figure><div class=\"wp-block-media-text__content\">\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/herpescureadvocacy.com\/2022\/03\/17\/herpes-cure-pipeline-2-0-2\/\">Herpes Cure Pipeline 2.0<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"http:\/\/www.herpescureadvocacy.com\/#newsletter\">Join waitlist for Herpes Cure Pipeline 3.0 Release Party<\/a><\/p>\n<\/div><\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n<\/div><\/div>\n<\/div><\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n","protected":false},"excerpt":{"rendered":"<p>The basics on the prevalence, epidemiology, and public health impact of Herpes Simplex Virus. Prevalence, Demographics, and Data on Herpes Simplex Virus 2018 NCHS Data Brief: Prevalence of Herpes Simplex<a class=\"more-link\" href=\"https:\/\/herpescureadvocacy.com\/herpes-simplex-virus-101-the-basics\/\">Continue reading <span class=\"screen-reader-text\">&#8220;Herpes Simplex Virus 101: The Basics&#8221;<\/span><\/a><\/p>\n","protected":false},"author":205069572,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_coblocks_attr":"","_coblocks_dimensions":"","_coblocks_responsive_height":"","_coblocks_accordion_ie_support":"","footnotes":""},"class_list":["post-2124","page","type-page","status-publish","hentry","entry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.9 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Herpes Simplex Virus 101: The Basics - Herpes Cure Advocacy<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/herpescureadvocacy.com\/herpes-simplex-virus-101-the-basics\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Herpes Simplex Virus 101: The Basics - Herpes Cure Advocacy\" \/>\n<meta property=\"og:description\" content=\"The basics on the prevalence, epidemiology, and public health impact of Herpes Simplex Virus. 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