{"id":242,"date":"2021-06-14T00:01:00","date_gmt":"2021-06-14T04:01:00","guid":{"rendered":"http:\/\/herpescureadvocacy.com\/2021\/07\/13\/current-herpes-cure-research-at-excision-biotherapeutics\/"},"modified":"2021-07-17T23:59:10","modified_gmt":"2021-07-18T03:59:10","slug":"current-herpes-cure-research-at-excision-biotherapeutics","status":"publish","type":"post","link":"https:\/\/herpescureadvocacy.com\/2021\/06\/14\/current-herpes-cure-research-at-excision-biotherapeutics\/","title":{"rendered":"Current Herpes Cure Research at Excision BioTherapeutics"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">Excision Bio has illustrated the possibility in developing a curative gene therapy using CRISPR in treating both active and latent HSV infection in the body. The company has stated that they plan to begin clinical trials in Q1 2023. <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Excision&#8217;s cutting edge CRISPR gene therapy platform is built on technology licensed from the Doudna Lab at UC Berkeley and the Khalili Lab at Temple University. They are the first company to remove HIV genomes from animals and generate functional cures for HIV.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The company&#8217;s primary focus at this point in time being curing HIV with CRISPR. The company is in the middle of filing their IND with the FDA for HIV clinical trials, which they plan to begin in 2021.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">In February 2021 Excision <a href=\"https:\/\/www.bizjournals.com\/sanfrancisco\/news\/2021\/02\/17\/hiv-aids-excision-biotherapeutics-herpes-hepatitis.html\">announced<\/a> $60 million raised in funding to focus on their research streams including HSV.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Updates on IND filing status can be found <a href=\"https:\/\/www.excision.bio\/technology\">here<\/a>.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Excision Bio has illustrated the possibility in developing a curative gene therapy using CRISPR in treating both active and latent HSV infection in the body. The company has stated that<a class=\"more-link\" href=\"https:\/\/herpescureadvocacy.com\/2021\/06\/14\/current-herpes-cure-research-at-excision-biotherapeutics\/\">Continue reading <span class=\"screen-reader-text\">&#8220;Current Herpes Cure Research at Excision BioTherapeutics&#8221;<\/span><\/a><\/p>\n","protected":false},"author":205069572,"featured_media":257,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_coblocks_attr":"","_coblocks_dimensions":"","_coblocks_responsive_height":"","_coblocks_accordion_ie_support":"","_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_feature_clip_id":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"{title}\n\n{excerpt}\n\n{url}","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":false,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2},"_wpas_customize_per_network":false,"jetpack_post_was_ever_published":false},"categories":[1],"tags":[42501519,2871574,5890257,103,88731,719338644],"class_list":["post-242","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-uncategorized","tag-crispr","tag-herpes-simplex-virus","tag-hsv-2","tag-news","tag-patients","tag-treatment","entry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.9 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Current Herpes Cure Research at Excision BioTherapeutics - Herpes Cure Advocacy<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/herpescureadvocacy.com\/2021\/06\/14\/current-herpes-cure-research-at-excision-biotherapeutics\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Current Herpes Cure Research at Excision BioTherapeutics - Herpes Cure Advocacy\" \/>\n<meta property=\"og:description\" content=\"Excision Bio has illustrated the possibility in developing a curative gene therapy using CRISPR in treating both active and latent HSV infection in the body. The company has stated thatContinue reading &quot;Current Herpes Cure Research at Excision BioTherapeutics&quot;\" \/>\n<meta property=\"og:url\" content=\"https:\/\/herpescureadvocacy.com\/2021\/06\/14\/current-herpes-cure-research-at-excision-biotherapeutics\/\" \/>\n<meta property=\"og:site_name\" content=\"Herpes Cure Advocacy\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/profile.php?id=100087212780212\" \/>\n<meta property=\"article:published_time\" content=\"2021-06-14T04:01:00+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2021-07-18T03:59:10+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2021\/07\/zlsw0sxxthsrkxriicdt_dsc_0345.jpg?fit=750%2C498&ssl=1\" \/>\n\t<meta property=\"og:image:width\" content=\"750\" \/>\n\t<meta property=\"og:image:height\" content=\"498\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Patient Advocate\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@herpesadvocate\" \/>\n<meta name=\"twitter:site\" content=\"@herpesadvocate\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Patient Advocate\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/herpescureadvocacy.com\\\/2021\\\/06\\\/14\\\/current-herpes-cure-research-at-excision-biotherapeutics\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/herpescureadvocacy.com\\\/2021\\\/06\\\/14\\\/current-herpes-cure-research-at-excision-biotherapeutics\\\/\"},\"author\":{\"name\":\"Patient Advocate\",\"@id\":\"https:\\\/\\\/herpescureadvocacy.com\\\/#\\\/schema\\\/person\\\/5a8a408f85fcdaa526d3173c93216d14\"},\"headline\":\"Current Herpes Cure Research at Excision BioTherapeutics\",\"datePublished\":\"2021-06-14T04:01:00+00:00\",\"dateModified\":\"2021-07-18T03:59:10+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/herpescureadvocacy.com\\\/2021\\\/06\\\/14\\\/current-herpes-cure-research-at-excision-biotherapeutics\\\/\"},\"wordCount\":152,\"commentCount\":1,\"publisher\":{\"@id\":\"https:\\\/\\\/herpescureadvocacy.com\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/herpescureadvocacy.com\\\/2021\\\/06\\\/14\\\/current-herpes-cure-research-at-excision-biotherapeutics\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/i0.wp.com\\\/herpescureadvocacy.com\\\/wp-content\\\/uploads\\\/2021\\\/07\\\/zlsw0sxxthsrkxriicdt_dsc_0345.jpg?fit=4219%2C2802&ssl=1\",\"keywords\":[\"Crispr\",\"Herpes Simplex Virus\",\"HSV-2\",\"News\",\"Patients\",\"Treatment\"],\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\\\/\\\/herpescureadvocacy.com\\\/2021\\\/06\\\/14\\\/current-herpes-cure-research-at-excision-biotherapeutics\\\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/herpescureadvocacy.com\\\/2021\\\/06\\\/14\\\/current-herpes-cure-research-at-excision-biotherapeutics\\\/\",\"url\":\"https:\\\/\\\/herpescureadvocacy.com\\\/2021\\\/06\\\/14\\\/current-herpes-cure-research-at-excision-biotherapeutics\\\/\",\"name\":\"Current Herpes Cure Research at Excision BioTherapeutics - 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UPenn\/BioNTech Clinical Trials: Latest updates and Q&A with Dr Harvey Friedman\u2026","rel":"","context":"With 1 comment","block_context":{"text":"With 1 comment","link":"https:\/\/herpescureadvocacy.com\/2022\/12\/01\/meet-the-experts\/#comments"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2021\/10\/img_1044.jpg?fit=1000%2C638&ssl=1&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2021\/10\/img_1044.jpg?fit=1000%2C638&ssl=1&resize=350%2C200 1x, https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2021\/10\/img_1044.jpg?fit=1000%2C638&ssl=1&resize=525%2C300 1.5x, https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2021\/10\/img_1044.jpg?fit=1000%2C638&ssl=1&resize=700%2C400 2x"},"classes":[]},{"id":6126,"url":"https:\/\/herpescureadvocacy.com\/2025\/07\/26\/crispr-and-herpes\/","url_meta":{"origin":242,"position":1},"title":"CRISPR and Herpes","author":"Patient Advocate","date":"July 26, 2025","format":false,"excerpt":"A tool to edit herpes out of the genome. Clustered Regularly Interspaced Short Palindromic Repeats CRISPR is an exciting new tool that scientists have used to edit genomes. It was discovered that different bacteria use CRISPR to defend themselves against viral infections, and we have now adopted similar techniques for\u2026","rel":"","context":"In &quot;Herpes Cure Research&quot;","block_context":{"text":"Herpes Cure Research","link":"https:\/\/herpescureadvocacy.com\/category\/herpes-cure\/"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2022\/10\/pexels-photo-4033152.jpg?fit=1200%2C800&ssl=1&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2022\/10\/pexels-photo-4033152.jpg?fit=1200%2C800&ssl=1&resize=350%2C200 1x, https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2022\/10\/pexels-photo-4033152.jpg?fit=1200%2C800&ssl=1&resize=525%2C300 1.5x, https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2022\/10\/pexels-photo-4033152.jpg?fit=1200%2C800&ssl=1&resize=700%2C400 2x, https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2022\/10\/pexels-photo-4033152.jpg?fit=1200%2C800&ssl=1&resize=1050%2C600 3x"},"classes":[]},{"id":169,"url":"https:\/\/herpescureadvocacy.com\/2021\/05\/24\/what-is-the-timeline-for-a-herpes-cure\/","url_meta":{"origin":242,"position":2},"title":"What is the timeline for a Herpes Cure?","author":"Patient Advocate","date":"May 24, 2021","format":false,"excerpt":"The most frequently asked question in our community? What is the timeline for a Herpes Cure? When will there be a herpes cure? There have always been companies working towards better treatments, vaccines, and cures for HSV-1 and HSV-2, and many have failed. But recently two events changed the possible\u2026","rel":"","context":"In \"Advocacy\"","block_context":{"text":"Advocacy","link":"https:\/\/herpescureadvocacy.com\/tag\/advocacy\/"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2021\/05\/winter-view.jpg?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2021\/05\/winter-view.jpg?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2021\/05\/winter-view.jpg?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2021\/05\/winter-view.jpg?resize=700%2C400&ssl=1 2x, https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2021\/05\/winter-view.jpg?resize=1050%2C600&ssl=1 3x, https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2021\/05\/winter-view.jpg?resize=1400%2C800&ssl=1 4x"},"classes":[]},{"id":2277,"url":"https:\/\/herpescureadvocacy.com\/2023\/05\/10\/herpes-keratitis-cure-advances-to-phase-3-clinical-trials-in-china\/","url_meta":{"origin":242,"position":3},"title":"Herpes Keratitis Cure advances to Phase 3 Clinical Trials in China","author":"Patient Advocate","date":"May 10, 2023","format":false,"excerpt":"BDGene Therapeutics is a Chinese biotech company based in Shanghai. BDgene now has approval to run Phase 3 trials (held in China) on their gene therapy cure for HSV-1 keratitis. The gene editing treatment for viral keratitis (BD111), developed based on BDmRNA delivery patent technology, has completed 3 human clinical\u2026","rel":"","context":"Similar post","block_context":{"text":"Similar post","link":""},"img":{"alt_text":"shallow focus photography of human eyes","src":"https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2023\/05\/pexels-photo-834783.jpeg?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2023\/05\/pexels-photo-834783.jpeg?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2023\/05\/pexels-photo-834783.jpeg?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2023\/05\/pexels-photo-834783.jpeg?resize=700%2C400&ssl=1 2x, https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2023\/05\/pexels-photo-834783.jpeg?resize=1050%2C600&ssl=1 3x, https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2023\/05\/pexels-photo-834783.jpeg?resize=1400%2C800&ssl=1 4x"},"classes":[]},{"id":1080,"url":"https:\/\/herpescureadvocacy.com\/2022\/04\/05\/hsv-scientists-give-herpes-impacted-communities-a-voice\/","url_meta":{"origin":242,"position":4},"title":"Herpes Scientists Give Impacted Communities a Voice","author":"Patient Advocate","date":"April 5, 2022","format":false,"excerpt":"The University of Washington Virology Division and the Vaccine and Infectious Disease Division at Fred Hutch Cancer Center have announced a new initiative for members of the communities affected by herpes simplex virus infection to join a new Community Advisory Board that will potentially inform future scientific research and\/or clinical\u2026","rel":"","context":"With 1 comment","block_context":{"text":"With 1 comment","link":"https:\/\/herpescureadvocacy.com\/2022\/04\/05\/hsv-scientists-give-herpes-impacted-communities-a-voice\/#comments"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2022\/04\/pexels-photo-3719037.jpeg?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2022\/04\/pexels-photo-3719037.jpeg?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2022\/04\/pexels-photo-3719037.jpeg?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2022\/04\/pexels-photo-3719037.jpeg?resize=700%2C400&ssl=1 2x, https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2022\/04\/pexels-photo-3719037.jpeg?resize=1050%2C600&ssl=1 3x, https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2022\/04\/pexels-photo-3719037.jpeg?resize=1400%2C800&ssl=1 4x"},"classes":[]},{"id":1297,"url":"https:\/\/herpescureadvocacy.com\/2022\/06\/29\/possible-herpes-keratitis-cure-takes-another-step-bdgene-of-china-applies-for-orphan-drug-designation-at-the-fda\/","url_meta":{"origin":242,"position":5},"title":"Possible herpes keratitis cure takes another step: BDGene of China applies for Orphan Drug Designation at the FDA","author":"Patient Advocate","date":"June 29, 2022","format":false,"excerpt":"Chinese company BDGene from Shanghai continues to lead in the global race for a herpes keratitis cure. The highly anticipated treatment, BD111 has reached a big milestone as it applied for Orphan Drug designation from the US FDA. Previously, BD111 has received international attention for its progress with a gene\u2026","rel":"","context":"Similar post","block_context":{"text":"Similar post","link":""},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2022\/06\/pexels-photo-4033148.jpg?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2022\/06\/pexels-photo-4033148.jpg?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2022\/06\/pexels-photo-4033148.jpg?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2022\/06\/pexels-photo-4033148.jpg?resize=700%2C400&ssl=1 2x, https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2022\/06\/pexels-photo-4033148.jpg?resize=1050%2C600&ssl=1 3x, https:\/\/i0.wp.com\/herpescureadvocacy.com\/wp-content\/uploads\/2022\/06\/pexels-photo-4033148.jpg?resize=1400%2C800&ssl=1 4x"},"classes":[]}],"_links":{"self":[{"href":"https:\/\/herpescureadvocacy.com\/wp-json\/wp\/v2\/posts\/242","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/herpescureadvocacy.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/herpescureadvocacy.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/herpescureadvocacy.com\/wp-json\/wp\/v2\/users\/205069572"}],"replies":[{"embeddable":true,"href":"https:\/\/herpescureadvocacy.com\/wp-json\/wp\/v2\/comments?post=242"}],"version-history":[{"count":1,"href":"https:\/\/herpescureadvocacy.com\/wp-json\/wp\/v2\/posts\/242\/revisions"}],"predecessor-version":[{"id":258,"href":"https:\/\/herpescureadvocacy.com\/wp-json\/wp\/v2\/posts\/242\/revisions\/258"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/herpescureadvocacy.com\/wp-json\/wp\/v2\/media\/257"}],"wp:attachment":[{"href":"https:\/\/herpescureadvocacy.com\/wp-json\/wp\/v2\/media?parent=242"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/herpescureadvocacy.com\/wp-json\/wp\/v2\/categories?post=242"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/herpescureadvocacy.com\/wp-json\/wp\/v2\/tags?post=242"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}